#triage

• ER stress UPR not yet baseline-positive as a mammalian longevity node 20260425154643000
• Heat-shock/chaperone augmentation is not yet baseline-positive as a mammalian longevity node 20260425154317000
• Proteasome augmentation is not yet baseline-positive as a longevity node 20260425154052000
• 不要把整类机制一刀切地排除 20260425153833000
• Mitochondrial interventions have direct lifespan-endpoint positives, but evidence is heterogeneous 20260425153808000
• Autophagy enhancement is not yet baseline-positive like rapamycin/mTOR 20260425153601000
• Rapamycin is a baseline-positive specific node; autophagy and mitochondria are not automatically longevity candidates 20260425153226000
• mTOR/rapamycin 优先于泛化自噬/线粒体作为长寿候选 20260425152830000
• 寿命终点优先于通路热度 20260425131208000