Iter-4360dd15-0138-fact-BOLERO-2-erratum-verbatim-pair
4360dd15 fact erratum verification knowledge
BOLERO-2 erratum 的摘要逐字对照(第 138 轮)
原句(被标错的摘要句)
"Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, patients with recurrence during or within 12 months of completion of adjuvant therapy, and irrespective of age."
修正句(erratum 替换句)
"Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, and irrespective of age."
可验证差异
* 被删除的唯一片段:"patients with recurrence during or within 12 months of completion of adjuvant therapy"
* 其余数值与主结论不变
* 这说明 erratum 是 subgroup wording correction,不是疗效数据修订
证据链
* 原文 PMC:https://pmc.ncbi.nlm.nih.gov/articles/PMC3898123/
* 勘误 PMC:https://pmc.ncbi.nlm.nih.gov/articles/PMC4713958/
* web 搜索结果已再次回显错误句开头,作为交叉校验
复现备注
将原句与修正句并排时,最小编辑是删除一个亚组描述短语;该删除不影响 PFS 数值、HR、P 值或其他亚组。