Iter-4360dd15-0143-fact-BOLERO-2-erratum-vertical-verbatim-pair

PMC4713958 与原文的逐字一行对照已闭环

子任务

从权威源直接抽取 BOLERO-2 论文原摘要句与勘误页修正句，验证二者的最小差异。

权威来源

- 原文：https://pmc.ncbi.nlm.nih.gov/articles/PMC3898123/
- 勘误：https://pmc.ncbi.nlm.nih.gov/articles/PMC4713958/

逐字对照

原句（PMC3898123 摘要）
''Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, patients with recurrence during or within 12 months of completion of adjuvant therapy, and irrespective of age.''

修正句（PMC4713958）
''Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, and irrespective of age.''

最小差分

删除片段：
''patients with recurrence during or within 12 months of completion of adjuvant therapy, ''

机器校验

Python 最长公共前后缀切分：
- common prefix = 549
- common suffix = 24
- removed = ''patients with recurrence during or within 12 months of completion of adjuvant therapy, ''
- added = ''
- reconstruct_ok = True

代码要点：用最长公共前缀/后缀定位中间差异，确认勘误仅做 scope wording correction，不改 PFS 数值。

结论

这条勘误只删掉了一个被误列入 prospectively defined subgroups 的短语；疗效数值、HR、P 值保持不变。