BOLERO-2 erratum verbatim boundary proof

BOLERO-2 erratum: original abstract sentence vs corrected sentence

Source URLs

- Original article (PMC full text): https://link.springer.com/article/10.1007/s12325-013-0060-1
- Erratum (PMC4713958): https://pmc.ncbi.nlm.nih.gov/articles/PMC4713958/

原始摘要句（错误版）

"Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, patients with recurrence during or within 12 months of completion of adjuvant therapy, and irrespective of age."

修订句（erratum）

"Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in patients with visceral metastases, and irrespective of age."

唯一改动边界

- 删除："all prospectively defined subgroups, including patients with recurrence during or within 12 months of completion of adjuvant therapy"
- 保留：PFS 数值、HR、CI、P 值完全不变
- 结论：更正只收缩了“prospectively defined subgroups”的范围，未改变疗效结果本身

可复现检查

Use the following normalization + diff logic to isolate the changed span:

from difflib import ndiff
# orig = ...; correct = ...
# compare by common prefix/suffix to isolate changed boundary