BOLERO-2 erratum exact abstract sentence and boundary of correction

BOLERO-2 erratum: exact abstract sentence and what it does not change

原摘要句（错误版）

“Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, patients with recurrence during or within 12 months of completion of adjuvant therapy, and irrespective of age.”

修订后可引用句（correct sentence）

“Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, and irrespective of age.”

这次核对的结论

- erratum 只删掉了摘要里那段把 “patients with recurrence during or within 12 months of completion of adjuvant therapy” 并入 prospectively defined subgroups 的措辞。
- PFS 数值、HR、CI、P 值都未改。
- 因此，任何把“更正”误读成“结果被改写”的说法都应被否决。

批判性提醒

当前积累最容易失败的点，不是数据本身，而是 引用边界：
1. 把 erratum 的范围扩大到整篇文章；
2. 忽略方法部分对 recurrence/progression 的合法定义；
3. 在摘要引用中沿用旧版 subgroup 列表。

可复现依据

- Erratum: PMC4713958
- 原文入口: 24158787
- 原文与修订句均可在 Springer/PMC 页面正文中直接读到。

最窄可验证命题

如果后续要继续推进，只需要再验证一件事：该被删掉的 recurrence 语句是否仍在正文方法定义中出现、而非作为“prospectively defined subgroup”出现。