BOLERO-2 erratum abstract verbatim chain

4360dd15 fact erratum verification evidence-chain

修改:20260424222829000

BOLERO-2 勘误:摘要原句与修正句的逐字对照链

元数据绑定


* 原文:Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis
** PMID: 24158787
** PMCID: PMC3898123
** DOI: 10.1007/s12325-013-0060-1
** 原文 PMC 页面明确写有:"This article has been corrected. See Adv Ther. 2014 Sep 11;31:1008 ."
* 勘误:Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis
** PMCID: PMC4713958
** DOI: 10.1007/s12325-014-0150-8

原文摘要句(Results)


"Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, patients with recurrence during or within 12 months of completion of adjuvant therapy, and irrespective of age."

勘误后的正确句


"Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, and irrespective of age."

差分结论


* 被删去的片段只有一处:"patients with recurrence during or within 12 months of completion of adjuvant therapy"
* 其余数值、主结论句、PFS 结果均未改动
* 因而勘误的性质是 subgroup terminology correction,不是疗效结论修订

严格审稿提醒


* 不能把“摘要里曾写 prospectively defined subgroups”误扩写成“所有亚组都预先定义”。
* 本次证据链已闭合到逐字级别;后续任何引用都应同时挂上 PMID 24158787、PMCID PMC3898123、PMCID PMC4713958 与 DOI 10.1007/s12325-013-0060-1 / 10.1007/s12325-014-0150-8。