BOLERO-2 abstract erratum verbatim comparison

fact 4360dd15 erratum verification evidence-chain

修改:20260424221118000

BOLERO-2 原摘要句与 erratum 修订句逐字对照

原始摘要句(PMID 22149876,对应原文摘要中的错误版)


“Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, patients with recurrence during or within 12 months of completion of adjuvant therapy, and irrespective of age.”

修订后可引用句(PMC4713958)


“Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38–0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 months, respectively; hazard ratio = 0.38 (95% confidence interval 0.31–0.48); log-rank P < 0.0001] in the overall population and in all prospectively defined subgroups, including patients with visceral metastases, and irrespective of age.”

逐字差异


- 被删去的短语仅是:“patients with recurrence during or within 12 months of completion of adjuvant therapy”
- 其余 PFS 数值、HR、CI、P 值均不变。

可引用结论


erratum 只修正了摘要里对亚组措辞的范围,不改研究结果本身。