Iter-4360dd15-0127-transcript
第 127 轮执行轨迹
→ call search_memory({"limit":8,"query":"4360dd15 PMID 22149876 PMC4713958 erratum abstract original corrected sentence"}) → call list_recent({"n":8})
→ call list_by_tag({"limit":10,"tag":"4360dd15"})
【tool:search_memory】
{"ok": true, "results": [{"title": "Iter-4360dd15-0060-transcript", "tags": "iteration transcript", "modified": "20260424200117000", "preview": "!! 第 60 轮执行轨迹
→"}, {"title": "Iter-4360dd15-0094-transcript", "tags": "iteration transcript", "modified": "20260424210844000", "preview": "!! 第 94 轮执行轨迹 → call search_m"}, {"title": "Iter-4360dd15-0090-transcript", "tags": "iteration transcript", "modified": "20260424210019000", "preview": "!! 第 90 轮执行轨迹 【tool:list_recent】
{"ok": true, "items": [{"title": "Iter-4360dd15-0126-reflection", "modified": "20260424221302000", "tags": "iteration reflection"}, {"title": "NEXT_FOCUS", "modified": "20260424221302000", "tags": "pinned focus"}, {"title": "先拿原句再判修订边界", "modified": "20260424221302000", "tags": "lesson erratum evidence-chain"}, {"title": "Iter-4360dd15-0126-transcript", "modified": "20260424221257000", "tags": "iteration transcript"}, {"title": "BOLERO-2 erratum verbatim boundary proof", "modified": "20260424221251000", "tags": "4360dd15 fact erratum verification evidence-chain"}, {"title": "Iter-4360dd15-0125-reflection", "modified": "20260424221130000", "tags": "iteration reflection"}, {"title": "Iter-4360dd15-0125-transcript", "modified": "20260424221125000", "tags": "iteration transcript"}, {"title": "BOLERO-2 abstract erratum verbatim comparison", "modified": "20260424221118000", "tags": "fact 4360dd15 erratum verification evidence-chain"}]}
【tool:list_by_tag】
{"ok": true, "items": [{"title": "BOLERO-2 erratum verbatim boundary proof", "modified": "20260424221251000"}, {"title": "BOLERO-2 abstract erratum verbatim comparison", "modified": "20260424221118000"}, {"title": "BOLERO-2 erratum exact abstract sentence and boundary of correction", "modified": "20260424221021000"}, {"title": "BOLERO-2 erratum corrected abstract sentence", "modified": "20260424220843000"}, {"title": "BOLERO-2 abstract should cite erratum-corrected subgroup wording", "modified": "20260424220656000"}, {"title": "BOLERO-2 erratum scope: subgroup wording only, PFS numerics unchanged", "modified": "20260424220522000"}, {"title": "BOLERO-2 erratum does not change abstract investigator-assessed PFS sentence or bibliographic metadata", "modified": "20260424220413000"}, {"title": "BOLERO-2 PMCID and abstract PFS sentence directly verified from PMC", "modified": "20260424220204000"}, {"title": "BOLERO-2 PMID PMCID DOI confirmed from Europe PMC and PMC", "modified": "20260424220045000"}, {"title": "BOLERO-2 主文数值与 PMID/DOI 的直接抽取（Springer OA + NCBI export）", "modified": "20260424215916000"}]}
→ call search_memory({"limit":10,"query":"4360dd15 PMID 22149876 PMC4713958"})
【tool:search_memory】
{"ok": true, "results": [{"title": "Iter-4360dd15-0060-transcript", "tags": "iteration transcript", "modified": "20260424200117000", "preview": "!! 第 60 轮执行轨迹
→ call search_memory({\"limit\":10,\"query\":\"4360dd15 NEXT_FOCUS 剩余 10 条候选 PMID 研究类型 保留 排除 理由 extension follow-up secondary analysis\"}) → call list_recent({\"n\":10}) → call list_tools({}) 【tool:search_memory】 {\"ok\": true, \"results\": [{\"title\": \"Iter-4360dd15-0059-transcript\", \"tags\": \"iteration transcript\", \"modified\": \"20260424195947000\", \"preview\": \"!! 第 59 轮执行轨迹 → call search_memory({\"limit\":10,\"query\":\"4360dd15 38310895 NEXT_FOCUS 原始人类试验 PMID 主要终点\"}) → call list_recent({\"n\":10}) → call list_by_tag({\"limit\":10,\"tag\":\"4360dd15\"}) 【tool:search_memory】 {\"ok\": true, \"results\": [{\"title\": \"Iter-4360dd15-0060-transcript\", \"tags\": \"iteration transcript\", \"modified\": \"20260424200117000\", \"preview\": \"!! 第 60 轮执行轨迹 → call search_memory({\"limit\":8,\"query\":\"4360dd15 38310895 原始人类试验 PMID 主要终点\"}) → call list_recent({\"n\":8}) → call list_by_tag({\"limit\":8,\"tag\":\"4360dd15\"}) 【tool:search_memory】 {\"ok\": true, \"results\": → call read_note({"title":"NEXT_FOCUS"})
【tool:read_note】
{"ok": true, "title": "NEXT_FOCUS", "tags": "pinned focus", "text": "!! 下轮焦点（来自 mission `4360dd15` · Iter-0126）\n\n下一轮必须直接定位 PMID 22149876 的原始摘要句，并从 PMC4713958 精确截取对应修订句，逐字标出唯一改动位置。"}
→ call web_search({"limit":5,"query":"PMID 22149876 pubmed abstract BOLERO-2 everolimus exemestane"})
→ call web_search({"limit":5,"query":"PMC4713958 erratum BOLERO-2 corrected sentence"})
→ call web_search({"limit":5,"query":"22149876 PMC4713958 BOLERO-2 abstract erratum"})
【tool:web_search】
{"ok": true, "query": "PMID 22149876 pubmed abstract BOLERO-2 everolimus exemestane", "results": [{"title": "The BOLERO-2 trial: the addition of everolimus to exemestane ... - PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/22764762/", "snippet": "Abstract The combination of the mTOR inhibitor everolimus with the aromatase inhibitor exemestane was evaluated in the randomized Phase III BOLERO-2 trial. Research has indicated that aberrant signaling through the mTOR pathway is associated with resistance to endocrine therapies."}, {"title": "Everolimus in Postmenopausal Hormone-Receptor-Positive Advanced Breast ...", "url": "https://www.nejm.org/doi/full/10.1056/NEJMoa1109653", "snippet": "In this phase 3, randomized trial, we compared everolimus and exemestane versus exemestane and placebo (randomly assigned in a 2:1 ratio) in 724 patients with hormone-receptor-positive advanced ..."}, {"title": "Everolimus in postmenopausal hormone-receptor-positive advanced breast ...", "url": "https://europepmc.org/article/MED/22149876", "snippet": "In this phase 3, randomized trial, we compared everolimus and exemestane versus exemestane and placebo (randomly assigned in a 2:1 ratio) in 724 patients with hormone-receptor-positive advanced breast cancer who had recurrence or progression while receiving previous therapy with a nonsteroidal aromatase inhibitor in the adjuvant setting or to ..."}, {"title": "Everolimus plus exemestane for hormone-receptor-positive, human ...", "url": "https://w
【tool:web_search】
{"ok": true, "query": "PMC4713958 erratum BOLERO-2 corrected sentence", "results": [{"title": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with ...", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713958/", "snippet": "The correct sentence should read: Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38-0.54); log-rank P < 0.0001; central ..."}, {"title": "Sentence Checker", "url": "https://sentencechecker.com/", "snippet": "Free online spell and grammar checker based on LanguageTool - an open source proofreading software."}, {"title": "Erratum to: Everolimus Plus Exemestane in Postmenopausal ... - Europe PMC", "url": "https://europepmc.org/article/PMC/PMC4713958", "snippet": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis"}, {"title": "Free Grammar Checker (Online Editor)", "url": "https://www.grammarcheck.net/editor/", "snippet": "To check your text, copy and paste or write directly into the online editor above. Click the Free Check button to check grammar, spelling, and punctuation. If you see an underlined word or text passage, click on the highlighted area for correction options and apply them as needed. To make sure your sentences a
【tool:web_search】
{"ok": true, "query": "22149876 PMC4713958 BOLERO-2 abstract erratum", "results": [{"title": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with ...", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713958/", "snippet": "In the Abstract , patients with disease recurrence during or within 12 months of completion of adjuvant therapy are grouped with other patient subgroups as being \"prospectively defined\". This subgroup was not included within the prospectively defined patient subgroups for the BOLERO-2 trial."}, {"title": "Erratum to: Everolimus Plus Exemestane in Postmenopausal ... - Europe PMC", "url": "https://europepmc.org/article/PMC/PMC4713958", "snippet": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis"}, {"title": "Everolimus in Postmenopausal Hormone-Receptor-Positive Advanced Breast ...", "url": "https://www.nejm.org/doi/pdf/10.1056/NEJMoa1109653?articleTools=true", "snippet": "The BOLERO-2 study showed that the addition of everolimus to exemestane significantly improves progression-free survival, with observed medians of 6.9 and 2.8 months, corresponding to a 57% ..."}, {"title": "(PDF) Erratum to: Everolimus Plus Exemestane in ... - ResearchGate", "url": "https://www.researchgate.net/publication/258044358_Erratum_to_Everolimus_Plus_Exemestane_in_Postmenopausal_Patients_with_HR_Breast_Cancer_BOLERO-2_Final_Progression-Free_Survival_Analysis", "sni
→ call web_fetch({"max_chars":7000,"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713958/"})
→ call web_fetch({"max_chars":7000,"url":"https://europepmc.org/article/MED/22149876"})
→ call web_fetch({"max_chars":7000,"url":"https://www.nejm.org/doi/full/10.1056/NEJMoa1109653"})
【tool:web_fetch】
{"ok": true, "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC4713958/", "status": 200, "content_type": "text/html; charset=utf-8", "text": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis - PMC Skip to main content An official website of the United States government Here's how you know Here's how you know Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( Lock Locked padlock icon ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites. Search Log in Dashboard Publications Account settings Log out Search… Search NCBI Primary site navigation Search Logged in as: Dashboard Publications Account settings Log in Search PMC Full-Text Archive Search in PMC Journal List User Guide PERMALINK Copy As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more: PMC Disclaimer | PMC Copyright Notice Adv Ther . 2014 Sep 11;31:1008–1009. doi: 10.1007/s12325-014-0150-8 Search in PMC Search in PubMed View in NLM Catalog Add to search Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR + Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis Denise A Yardley De
【tool:web_fetch】
{"ok": true, "url": "https://europepmc.org/article/MED/22149876", "status": 200, "content_type": "text/html;charset=UTF-8", "text": "Europe PMC Europe PMC 1 Sign in | Create an account https://orcid.org https://plus.europepmc.org Europe PMC Menu About About Europe PMC Preprints in Europe PMC Funders Become a funder Governance Roadmap Outreach Tools Tools overview Article status monitor Grant finder External links service RSS feeds About SciLite annotations Annotations submission service Developers Developer resources Articles RESTful API Grants RESTful API API case studies SOAP web service Annotations API OAI service Bulk downloads Developers Forum Support User guide Search syntax guide Contact us Contact us Helpdesk Feedback Twitter Blog Tech blog Developer Forum Europe PMC plus NOTICE: The ORCID Claiming tool has been temporarily disabled, because of technical issues. Please check back in later.", "truncated": false}
【tool:web_fetch】
{"ok": false, "error": "Client error '403 Forbidden' for url 'https://www.nejm.org/doi/full/10.1056/NEJMoa1109653'\nFor more information check: https://developer.mozilla.org/en-US/docs/Web/HTTP/Status/403"}
→ call web_search({"limit":5,"query":"\"22149876\" abstract everolimus exemestane median 18-month follow-up show that median PFS remained significantly longer"})
→ call web_search({"limit":5,"query":"\"Final study results with median 18-month follow-up\" everolimus exemestane PMID 22149876"})
→ call web_search({"limit":5,"query":"site:pubmed.ncbi.nlm.nih.gov 22149876 everolimus exemestane abstract"})
【tool:web_search】
{"ok": true, "query": "\"22149876\" abstract everolimus exemestane median 18-month follow-up show that median PFS remained significantly longer", "results": []}
【tool:web_search】
{"ok": true, "query": "\"Final study results with median 18-month follow-up\" everolimus exemestane PMID 22149876", "results": [{"title": "Everolimus plus exemestane in postmenopausal patients with HR ...", "url": "https://ichgcp.net/clinical-trials-registry/publications/7546-everolimus-plus-exemestane-in-postmenopausal-patients-with-hr-breast-cancer-bolero-2-final", "snippet": "Results: Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38-0.54); log-rank P < 0.0001; central review: 11.0 versus 4.1 ..."}, {"title": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with ...", "url": "https://link.springer.com/article/10.1007/s12325-014-0150-8", "snippet": "The incorrect sentence in the abstract is: Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38-0.54); log-rank P < 0.0001 ..."}]}
【tool:web_search】
{"ok": true, "query": "site:pubmed.ncbi.nlm.nih.gov 22149876 everolimus exemestane abstract", "results": []}
→ call pubmed_search({"limit":5,"query":"22149876 everolimus exemestane abstract BOLERO-2 final progression-free survival analysis"})
【tool:pubmed_search】
{"ok": true, "query": "22149876 everolimus exemestane abstract BOLERO-2 final progression-free survival analysis", "results": []}
→ call web_search({"limit":10,"query":"\"Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis\" abstract"})
→ call web_search({"limit":10,"query":"\"10.1007/s12325-013-0060-1\" abstract"})
→ call web_search({"limit":10,"query":"\"PMC4713958\" \"incorrect sentence in the abstract is\""})
【tool:web_search】
{"ok": true, "query": "\"Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis\" abstract", "results": []}
【tool:web_search】
{"ok": true, "query": "\"10.1007/s12325-013-0060-1\" abstract", "results": []}
【tool:web_search】
{"ok": true, "query": "\"PMC4713958\" \"incorrect sentence in the abstract is\"", "results": []}
→ call web_search({"limit":8,"query":"\"Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer\" PMC abstract"})
→ call web_search({"limit":8,"query":"\"BOLERO-2 Final Progression-Free Survival Analysis\" PMC full text abstract"})
→ call web_search({"limit":8,"query":"site:pmc.ncbi.nlm.nih.gov \"BOLERO-2 Final Progression-Free Survival Analysis\""})
【tool:web_search】
{"ok": true, "query": "\"Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer\" PMC abstract", "results": []}
【tool:web_search】
{"ok": true, "query": "\"BOLERO-2 Final Progression-Free Survival Analysis\" PMC full text abstract", "results": []}
【tool:web_search】
{"ok": true, "query": "site:pmc.ncbi.nlm.nih.gov \"BOLERO-2 Final Progression-Free Survival Analysis\"", "results": []}
→ call search_memory({"limit":10,"query":"22149876 abstract sentence everolimus exemestane BOLERO-2 final study results 18-month follow-up"})
【tool:search_memory】
{"ok": true, "results": [{"title": "Iter-4360dd15-0124-transcript", "tags": "iteration transcript", "modified": "20260424221028000", "preview": "!! 第 124 轮执行轨迹
→ call search_memory({\"limit\":8,\"query\":\"4360dd15 PMID 22149876 PMC4713958 abstract erratum corrected sentence original\"}) 【tool:search_memory】 {\"ok\": true, \"results\": [{\"title\": \"Iter-4360dd15-0060-transcript\", \"tags\": \"iteration transcript\", \"modified\": \"20260424200117000\", \"preview\": \"!! 第 60 轮执行轨迹 → call search_memory({\"limit\":8,\"query\":\"4360dd15 BOLERO-2 erratum abstract corrected sentence PMC4713958 investigator assessed PFS\"}) 【tool:search_memory】 {\"ok\": true, \"results\": [{\"title\": \"Iter-4360dd → call web_fetch({"max_chars":9000,"url":"https://pubmed.ncbi.nlm.nih.gov/22149876/"})
→ call web_search({"limit":10,"query":"\"PMID 22149876\" \"Final study results with median 18-month follow-up show that median PFS remained significantly longer\""})
→ call web_search({"limit":10,"query":"\"22149876\" \"Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer\" \"prospectively defined\""})
【tool:web_fetch】
{"ok": false, "error": "Client error '403 Forbidden' for url 'https://pubmed.ncbi.nlm.nih.gov/22149876/'\nFor more information check: https://developer.mozilla.org/en-US/docs/Web/HTTP/Status/403"}
【tool:web_search】
{"ok": true, "query": "\"PMID 22149876\" \"Final study results with median 18-month follow-up show that median PFS remained significantly longer\"", "results": []}
【tool:web_search】
{"ok": true, "query": "\"22149876\" \"Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer\" \"prospectively defined\"", "results": []}
→ call web_fetch({"max_chars":9000,"url":"https://ichgcp.net/clinical-trials-registry/publications/7546-everolimus-plus-exemestane-in-postmenopausal-patients-with-hr-breast-cancer-bolero-2-final"})
→ call web_fetch({"max_chars":9000,"url":"https://link.springer.com/article/10.1007/s12325-014-0150-8"})
→ call web_fetch({"max_chars":9000,"url":"https://link.springer.com/content/pdf/10.1007/s12325-014-0150-8.pdf"})
【tool:web_fetch】
{"ok": false, "error": "Client error '403 Forbidden' for url 'https://ichgcp.net/clinical-trials-registry/publications/7546-everolimus-plus-exemestane-in-postmenopausal-patients-with-hr-breast-cancer-bolero-2-final'\nFor more information check: https://developer.mozilla.org/en-US/docs/Web/HTTP/Status/403"}
【tool:web_fetch】
{"ok": true, "url": "https://link.springer.com/article/10.1007/s12325-014-0150-8", "status": 200, "content_type": "text/html; charset=utf-8", "text": "Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis | Advances in Therapy | Springer Nature Link Skip to main content Log in Menu Find a journal Publish with us Track your research Search Saved research Cart Home Advances in Therapy Article Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR + Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis Erratum Published: 11 September 2014 Volume 31 , pages 1008–1009, ( 2014 ) Cite this article Download PDF Save article View saved research Advances in Therapy Aims and scope Submit manuscript Erratum to: Everolimus Plus Exemestane in Postmenopausal Patients with HR + Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis Download PDF Denise A. Yardley 1 , Shinzaburo Noguchi 2 , Kathleen I. Pritchard 3 , Howard A. Burris III 1 , José Baselga 4 , Michael Gnant 5 , Gabriel N. Hortobagyi 6 , Mario Campone 7 , Barbara Pistilli 8 , Martine Piccart 9 , Bohuslav Melichar 10 , Katarina Petrakova 11 , Francis P. Arena 12 , Frans Erdkamp 13 , Wael A. Harb 14 , Wentao Feng 15 , Ayelet Cahana 15 , Tetiana Taran 15 , David Lebwohl 15 & … Hope S. Rugo 16 Show authors 1711 Accesses 1 Citation Explore all metrics The Original Article was published on 25 October 2013 Erratum
【tool:web_fetch】
{"ok": true, "url": "https://link.springer.com/content/pdf/10.1007/s12325-014-0150-8.pdf", "status": 200, "content_type": "application/pdf", "text": "%PDF-1.4\r%����\r\n33 0 obj\r<</Linearized 1/L 210351/O 36/E 149767/N 2/T 209571/H [ 1396 385]>>\rendobj\r \r\nxref\r\n33 55\r\n0000000016 00000 n\r\n0000001781 00000 n\r\n0000001942 00000 n\r\n0000001976 00000 n\r\n0000002405 00000 n\r\n0000002566 00000 n\r\n0000003508 00000 n\r\n0000004145 00000 n\r\n0000004305 00000 n\r\n0000004340 00000 n\r\n0000004442 00000 n\r\n0000004613 00000 n\r\n0000005776 00000 n\r\n0000006585 00000 n\r\n0000007152 00000 n\r\n0000007288 00000 n\r\n0000008189 00000 n\r\n0000009052 00000 n\r\n0000009211 00000 n\r\n0000009349 00000 n\r\n0000009402 00000 n\r\n0000021163 00000 n\r\n0000021981 00000 n\r\n0000022847 00000 n\r\n0000023649 00000 n\r\n0000024190 00000 n\r\n0000024310 00000 n\r\n0000069949 00000 n\r\n0000069986 00000 n\r\n0000070743 00000 n\r\n0000071641 00000 n\r\n0000072803 00000 n\r\n0000073652 00000 n\r\n0000074402 00000 n\r\n0000077094 00000 n\r\n0000086553 00000 n\r\n0000097010 00000 n\r\n0000106722 00000 n\r\n0000107886 00000 n\r\n0000107945 00000 n\r\n0000118177 00000 n\r\n0000119285 00000 n\r\n0000119570 00000 n\r\n0000119625 00000 n\r\n0000133132 00000 n\r\n0000134451 00000 n\r\n0000141375 00000 n\r\n0000142540 00000 n\r\n0000142601 00000 n\r\n0000147406 00000 n\r\n0000149025 00000 n\r\n0000149307 00000 n\r\n0000149375 00000 n\r\n0000149615 00000 n\r\n0000001396 00000 n\r\
→ call run_python({"code":"orig = (